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Abstract #1802

Comparison of Liver Apparent Diffusion Coefficient (ADC) Measurement Using Single-shot and Multi-shot Diffusion-weighted EPI

Liyuan Liang1, Hing Chiu Chang1, and Edward S. Hui1

1Department of Diagnostic Radiology, The University of Hong Kong, Hong Kong, Hong Kong

Diffusion-weighted imaging has been shown useful in measuring liver apparent diffusion coefficient (ADC) that can provide valuable information for clinical diagnosis. Single-shot diffusion-weighted echo-planar imaging (ssDW-EPI) is the preferred acquisition technique for ADC measurement on clinical MRI scanner. Recently, a multiplexed sensitivity encoding (MUSE) framework has been developed to reconstruct high-quality multi-shot DW-EPI (msDW-EPI) image in brain. In this study, we aim to evaluate the msDW-EPI technique on liver ADC measurement by quantitatively comparing measured ADC values obtained from either msDW-EPI or ssDW-EPI.

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