Meeting Banner
Abstract #1848

Probing Structure of Normal and Malignant Prostate Tissue before and after Radiation Therapy with Luminal Water Fraction and Diffusion-Weighted MRI

Dominic Carlin1, Matthew Orton1, David J Collins1,2, and Nandita M deSouza1,2

1Cancer Research UK Imaging Centre, The Institute of Cancer Research, Sutton, United Kingdom, 2MRI Unit, The Royal Marsden Hospital NHS Foundation Trust, Sutton, United Kingdom

Luminal Water Fraction (LWF) is higher in peripheral than transitional zone of the untreated prostate; in comparison, it is significantly reduced in tumors. LWF is correlated with ADC in untreated non-malignant prostate. LWF is not correlated with ADC in tumors or in post irradiated prostate indicating that the morphological factors affecting LWF and ADC in these tissues are independent.

This abstract and the presentation materials are available to members only; a login is required.

Join Here