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Abstract #1850

Prostate cancers invisible on multi-parametric MRI: Pathologic feature in correlation with whole mount prostatectomy

Aritrick Chatterjee1, Alexander Gallan2, Tatjana Antic2, Gregory S Karczmar1, and Aytekin Oto1

1Department Of Radiology, University of Chicago, Chicago, IL, United States, 2Department Of Pathology, University of Chicago, Chicago, IL, United States

This study investigates why some prostate cancers are not identified on mpMRI using ground truth reference from whole mount prostatectomy specimens. Unidentified cancers tend to exhibit lower Gleason grade and pathologic stage, smaller size, lower density of glands compared to surrounding tissue (sparse cancer lesions) and have different tissue composition, specifically higher lumen (associated with high ADC and T2) and lower epithelium (associated with low ADC and T2) compared to cancer lesions identified on MRI.

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