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Abstract #1858

Diffusion-Weighted MRI for Non-Contrast Breast Screening: Lesion Conspicuity on Computed vs. Acquired High b-Value Images

Michaela R DelPriore1, Debosmita Biswas1, Madeline C Dang1, Adrienne E Kim1, Habib Rahbar1, and Savannah C Partridge1

1Radiology, University of Washington, Seattle, WA, United States

On breast DWI, the relative signal intensity of a lesion can be increased by exploiting the differences in signal decay between tumor and normal tissue at higher b values. Computing high b-value images rather than acquiring them directly can increase lesion conspicuity and decrease scan times, improving the potential utility of breast DWI for non-contrast screening. In women with invasive breast cancer, we investigated the differences in lesion conspicuity across b-values and between acquired and computed diffusion weighted images. Our findings showed maximal lesion conspicuity at higher b-values (1200-1500s/mm2), with acquired images generally providing higher conspicuity than computed images.

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