Abstract #1933

Skeletal Muscle Adipose Tissue Quantification in Diabetic Peripheral Neuropathy

Amanda Ho¹, Shannon Haas¹, Antonio Convit², Kenneth Mroczek³, Jill Slade⁴, Prodromos Parasoglou¹, and Ryan Brown^1,5,6

¹Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, NY, United States, ²Department of Psychiatry, New York University School of Medicine, New York, NY, United States, ³Department of Orthopaedic Surgery, New York University Langone Hospital for Joint Diseases, New York, NY, United States, ⁴Department of Radiology, Michigan State University, East Lansing, MI, United States, ⁵Center for Advanced Imaging Innovation and Research (CAI2R), Department of Radiology, New York University School of Medicine, New York, NY, United States, ⁶Sackler Institute of Graduate Biomedical Sciences, New York University School of Medicine, New York, NY, United States

Diabetic peripheral neuropathy (DPN) is a common and serious complication of diabetes, where persistent hyperglycemia impairs metabolic and microvascular function, ultimately resulting in fatty infiltration. Quantitative adipose measurements using MRI may provide a useful tool to evaluate the effects of therapeutic intervention. We tested a chemical-shift based technique to measure skeletal muscle fatty infiltration in a cohort with DPN. Fatty infiltration was found to be increased in the ankle plantar flexors of DPN patients, with significant elevation detected in the medial gastrocnemius muscle.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.