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Abstract #1954

Pseudo spiral compressed sensing accelerated whole-heart 4D flow MRI: validation against EPI readout

Carmen PS Blanken1, Lukas M Gottwald1, Jos JM Westenberg2, Eva S Peper1, Bram F Coolen1, Gustav J Strijkers1, Aart J Nederveen1, R Nils Planken1, and Pim van Ooij1

1Amsterdam University Medical Centers, location AMC, Amsterdam, Netherlands, 2Leiden University Medical Center, Leiden, Netherlands

4D flow MRI facilitates detailed evaluation of cardiac hemodynamics in patients with cardiovascular disease. In this study, we investigated the performance of pseudo spiral compressed sensing (CS) accelerated whole-heart 4D flow MRI in a comparison with a clinically used EPI readout. CS-accelerated 4D flow MRI yielded similar results to EPI-accelerated 4D flow MRI in terms of velocity vector fields during ventricular ejection and filling and led to consistent blood flow measurements across heart valves. Our data suggest that CS 4D flow MRI has the potential to be accelerated even further for quantitative whole-heart hemodynamic imaging.

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