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Abstract #1964

Effect of inflow and in-plane saturation in SASHA and MOLLI T1 and T1* maps in a perfusion phantom and in-vivo

Ingo Hermann1, Tanja Uhrig1, Jorge Chacon-Caldera1, Mehmet Akçakaya2,3, Lothar R. Schad1, and Sebastian Weingärtner1,2,3

1Computer Assisted Clinical Medicine, University Medical Center Mannheim, Heidelberg University, Mannheim, Germany, 2Electrical and Computer Engineering, University of Minnesota, Minneapolis, MN, United States, 3Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States

Aim of this work was to evaluate the effect of flow on blood T1 measurement considering inflow of non-inverted spins. Experiments using a flow phantom demonstrate shorter T1 for increasing flow velocity, with high reproducibility. In-vivo measurements show major variations throughout the cardiac cycle, validating the flow sensitivity observed in phantom measurements.

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