Abstract #1964

Effect of inflow and in-plane saturation in SASHA and MOLLI T1 and T1* maps in a perfusion phantom and in-vivo

Ingo Hermann¹, Tanja Uhrig¹, Jorge Chacon-Caldera¹, Mehmet Akçakaya^2,3, Lothar R. Schad¹, and Sebastian Weingärtner^1,2,3

¹Computer Assisted Clinical Medicine, University Medical Center Mannheim, Heidelberg University, Mannheim, Germany, ²Electrical and Computer Engineering, University of Minnesota, Minneapolis, MN, United States, ³Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States

Aim of this work was to evaluate the effect of flow on blood T₁ measurement considering inflow of non-inverted spins. Experiments using a flow phantom demonstrate shorter T₁ for increasing flow velocity, with high reproducibility. In-vivo measurements show major variations throughout the cardiac cycle, validating the flow sensitivity observed in phantom measurements.

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