Abstract #1968

An application of the myocardial strain analysis method based on the deformation registration algorithm (DRA) in heart transplantation

Xuehua Shen¹, Yating Yuan¹, Mingxing Xie², Li Zhang², Wei Sun², Jia Liu¹, Xiaoyue Zhou³, Jing Song¹, and Bo Liang¹

¹Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, ²Department of Ultrasound, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, ³MR Collaboration, Siemens Healthcare Ltd., Shanghai, China., Shanghai, China

With the development of cardiac magnetic resonance(CMR), there have been various methods to quantify myocardium. As a novel method, deformation registration algorithm (DRA) has been confirmed in many cardiac diseases. In this article, we use this method to analyze the wall deformation of orthotopic heart transplantation(HTx). We found that though left ventricular ejection fraction (LVEF) have no significant difference between the HTx patients and the healthy volunteers, the left ventricular (LV) peak longitudinal strain (LV Ell) and LV peak systolic longitudinal strain rate have significant decrease in HTx patients, indicating that the ventricular deformation is more sensitive than LVEF in response to the myocardial diseases.

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