Abstract #1972

Experimental Validation of 4D Flow MRI for the Assessment of Flow Dynamics within a Patient-Specific Intracranial Aneurysm Model using Tomographic Particle Image Velocimetry

Rafael Medero^1,2, Katrina L. Ruedinger³, and Alejandro Roldán-Alzate^1,2,3

¹Mechanical Engineering, University of Wisconsin-Madison, Madison, WI, United States, ²Radiology, University of Wisconsin-Madison, Madison, WI, United States, ³Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, United States

4D flow MRI has shown to be a feasible tool for assessing hemodynamics in different vascular territories with high spatial resolution. This study aimed to compare velocity components and magnitudes within a patient-specific intracranial aneurysm in-vitro model using 4D Flow MRI and a ground truth experimental technique, tomographic particle image velocimetry (tomo-PIV). Tomo-PIV offers higher temporal and spatial resolution allowing the assessment of intra-cycle differences caused by pulsatile flow. This analysis was done to assess the ability of 4D Flow MRI to capture the complex flows within an intracranial aneurysm considering the cardiac cycle averaging of the data.

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