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Abstract #1999

Assessment of Pulmonary Hypertension using 4D flow and SSFP MRI

Daniel Gordon1, Muhannad Abbasi1, Carson Herman1, Michael Markl1, Pascale Aouad1, Jeremy Collins2, Roberto Sarnari1, Benjamin Freed1, Michael Cuttica1, Sanjiv Shah1, and James Carr1

1Northwestern University, Chicago, IL, United States, 2Mayo Clinic, Rochester, MN, United States

Right heart catheterization (RHC) is the current gold standard for the diagnosis of pulmonary hypertension (PHTN). However, the use of invasive and ionizing procedures during RHC has driven research to find alternative ways for PHTN assessment using MRI. We propose time resolved 3D imaging (4D flow) and SSFP cardiac MRI as an alternative method for assessing hemodynamics for PHTN. Using One-way Analysis of Variance (ANOVA), inter-observer variability, and post hoc analysis our findings indicate the possibility of MRI to detect hemodynamic changes among various groups of PHTN and healthy controls which could lead to successful diagnostic distinctions between groups.

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