Abstract #2010

Assessing myocardial infarct size by novel TRAFFn relaxation time method in lymphatic insufficient mice

Elias Yla-Herttuala¹, Taina Vuorio¹, Svetlana Laidinen¹, Seppo Yla-Herttuala^1,2, and Timo Liimatainen^3,4

¹A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland, ²Heart Center, Kuopio University Hospital, Kuopio, Finland, ³Research unit of medical imaging, physics and technology, University of Oulu, Oulu, Finland, ⁴Department of diagnostic radiology, Oulu University Hospital, Oulu, Finland

We applied novel RAFFn relaxation times (T_RAFF2 and T_RAFF4), T_1ρ and T₂ to study effects of cardiac lymphatic system in myocardial infarct (MI). Infarct size based on the T_RAFF4 relaxation time maps was significantly larger in earlier time points post MI in wild-type compared to lymphatic insufficient mice groups. No differences were found in relaxation times between groups. Area-of-overestimation (AOE) values remained stable in lymphatic insufficient group while in wild-type group a decreasing trend of AOE was observed. We conclude that effects of lymphatics after MI can be detected based on infarct size difference measured with different relaxation times.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.