Abstract #2074

Quantitative measurements of decreased arterial collateralization and branching in peripheral artery disease.

Niranjan Balu¹, Li Chen², Thoetphum Benyakorn¹, Daniel S Hippe¹, Henrik Haraldsson³, Warren Gasper³, David Saloner³, Chun Yuan¹, and Thomas Hatsukami⁴

¹Radiology, University of Washington, Seattle, WA, United States, ²Electrical Engineering, University of Washington, Seattle, WA, United States, ³University of California SanFrancisco, San Francisco, CA, United States, ⁴Surgery, University of Washington, Seattle, WA, United States

The extent of collateralization/branching (CB) of lower limb vessels in peripheral artery disease (PAD) can inform risk of ischemia and response to revascularization. However quantitative imaging metrics of CB have not been assessed in the setting of severe PAD. We developed automated quantitative measurements of lower limb vascular morphology (pCafe) and compared CB in patients undergoing revascularization for PAD. Assessment of pCafe metrics in severe PAD suggests CB is increased with occlusion compared to stenosis indicating compensatory CB development.

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