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Abstract #2089

Irregularity of Carotid Atherosclerotic Plaque Determined by Multidimensional Magnetic Resonance Imaging Stratifies the Risk of Acute Cerebral Infarction

Dan Zhou1, Dong Liu2, Jin Li2, and Xihai Zhao3

1Department of Radiology, Nanjing BenQ Hospital, Nanjing, China, 2Nanjing Medical University, Nanjing, China, 3Center for Biomedical Imaging research, Department of Biomedical Engineering, Tsinghua University School of Medicine, Beijing, China

Carotid plaque surface features including surface irregularities and ulceration represent an important indicator for plaque vulnerability and are associated with the occurrence of neurological symptoms1-2. This study aimed to determine the association between surface irregularity of carotid plaque on MR images at multi-dimensions and acute ischemic stroke. Ninety-seven symptomatic patients with atherosclerotic plaque in carotid artery determined by ultrasound imaging were enrolled and underwent MR imaging for carotid artery and brain. We found that the irregularity information at multi-dimensions which combined the axial and oblique images had stronger predictive value for acute ischemic lesion than axial images alone.

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