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Abstract #2100

Quantitative Multi-contrast Vessel Wall Imaging in the Carotid Arteries: Preliminary Results on Reproducibility in Healthy Volunteers

Axel J. Krafft1, Christian Licht1, Lilli Kaufhold2,3, Christoph Strecker4, Markus Huellebrand2,3, Jürgen Hennig1, Andreas Harloff4, Anja Hennemuth3, and Ute Ludwig1

1Radiology, Medical Physics, Medical Center – University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany, 2Fraunhofer MEVIS, Bremen, Germany, 3Institute for Imaging Science and Computational Modelling in Cardiovascular Medicine, Charité - Universitaetsmedizin Berlin, Berlin, Germany, 4Neurology, Medical Center – University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany

Internal carotid artery stenosis is a major source of ischemic stroke. Assessment of plaque formation and longitudinal progression necessitates reproducibility of imaging and post-processing methods. In this study, preliminary results on the reproducibility of wall thickness measurements using 3D multi-contrast vessel wall imaging at two different time points in healthy volunteers are presented. Between the two exams, relative deviations of the vessel wall thickness were mostly below 10% and below 15% when comparing different sequences. In conclusion, reproducible assessment of the carotid arteries with multi-contrast vessel wall imaging is feasible.

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