Abstract #2100

Quantitative Multi-contrast Vessel Wall Imaging in the Carotid Arteries: Preliminary Results on Reproducibility in Healthy Volunteers

Axel J. Krafft¹, Christian Licht¹, Lilli Kaufhold^2,3, Christoph Strecker⁴, Markus Huellebrand^2,3, Jürgen Hennig¹, Andreas Harloff⁴, Anja Hennemuth³, and Ute Ludwig¹

¹Radiology, Medical Physics, Medical Center – University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany, ²Fraunhofer MEVIS, Bremen, Germany, ³Institute for Imaging Science and Computational Modelling in Cardiovascular Medicine, Charité - Universitaetsmedizin Berlin, Berlin, Germany, ⁴Neurology, Medical Center – University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany

Internal carotid artery stenosis is a major source of ischemic stroke. Assessment of plaque formation and longitudinal progression necessitates reproducibility of imaging and post-processing methods. In this study, preliminary results on the reproducibility of wall thickness measurements using 3D multi-contrast vessel wall imaging at two different time points in healthy volunteers are presented. Between the two exams, relative deviations of the vessel wall thickness were mostly below 10% and below 15% when comparing different sequences. In conclusion, reproducible assessment of the carotid arteries with multi-contrast vessel wall imaging is feasible.

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