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Abstract #2113

Highly Accelerated Balanced SSFP Cardiac Cine 3D-DENSE Quantifies Human 3D Myocardial Strain

Ronald J. Beyers1, Nouha Salibi1, and Thomas S. Denney1

1MRI Research Center, Auburn University, Auburn University, AL, United States

Quantification of 2D and 3D myocardial strain at cine frame-rates has been previously demonstrated with echo-planar and spiral sequence versions of Displacement Encoding with Stimulated Echoes (DENSE). However, these non-conventional acquisition methods, with their sensitivities to off-resonance, has hindered their integration into mainstream cardiac MRI application. Here we present a more conventional, but highly accelerated, balanced SSFP (bSSFP) version of Cardiac Cine 3D-DENSE for application to human subjects. In vivo human scans at 3T demonstrated good agreement of myocardial radial (Err), circumferential (Ecc) and longitudinal Ell) strain values between bSSFP 3D-DENSE to those reported in previous literature.

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