Balanced steady-state free precession imaging distinguishes the non-compacted left ventricular (LV) myocardial trabeculation (NC) from compacted myocardium (C). However, current diagnostic criterion (NC/C length ratio > 2.3) for left ventricular non-compaction (LVNC) suffers from subjective variability and tends to over-diagnose. Cumulative perimetric ratio (CPR) derived from epi and endocardial contours routinely drawn for LV functional analysis provides comprehensive measure of irregularity and extent of the LV trabeculations overcoming the inherent morphologic variability from base to apex. CPR has a potential to serve as a valuable biomarker for prominent trabeculations, complementary to NC/C length and mass ratios.
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