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Abstract #2189

Evaluation of the performance of voxel-wise myocardial perfusion quantification methods using a traceable phantom

Loïc Coquelin1, Géraldine Ebrard1, Judith Lehnert2, Nadia Smith3, Xenios Milidonis4, Tobias Schaeffter2,5, and Amedeo Chiribiri4

1Department of Mathematics and Statistics, Laboratoire National de Métrologie et d'Essais (LNE), Trappes, France, 2Division of Medical Physics and Metrological Information Technology, Physikalisch-Technische Bundesanstalt (PTB), Braunschweig und Berlin, Berlin, Germany, 3Data Science, National Physical Laboratory (NPL), Teddington, United Kingdom, 4Cardiovascular Imaging, King’s College London, London, United Kingdom, 5Biomedical Engineering, King’s College London, London, United Kingdom

Assessing and comparing myocardial imaging methodologies require the use of a physical standard. A novel 3D printed cardiac phantom mimicking transmural myocardial perfusion gradients is used in this study, first to evaluate the repeatability of phase contrast MRI (PC-MRI) measurements and then, to compare two common methods for perfusion quantification using dynamic contrast enhanced MRI (DCE-MRI) measurements: the dual bolus and the model-based approach.

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