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Abstract #2197

DANTE-Prepared FLASH: Three-Dimensional Vessel Wall Imaging Of ApoE-/- Mouse at 7 Tesla

Yuanbo Yang1, Zhonghao Li2, Yingjie Mei3, Ming Zhao2, Guoxi Xie4, and Yanqiu Feng1

1School of Biomedical Engineering, Guangdong Provincial Key Laborary of Medical Image Processing, Southern Medical University, Guangzhou, People's Republic of China, Guangzhou, China, 2Department of Pathophysiology, Key Lab for Shock and Microcirculation Research of Guangdong, Southern Medical University, Guangzhou, 510515, PR China, Guangzhou, China, 3Philips Healthcare, Guangzhou, China, Guangzhou, China, 4Department of Biomedical Engineering, School of Basic Sciences, Guangzhou Medical University, Guangzhou, China

There is a growing preclinical demand for methods to characterize atherosclerotic plaque in vivo. Recently proposed DANTE for dark-blood preparation successfully in vessel wall imaging. However, previous studies were performed at 3T and used for vessel wall imaging of human. It remains unclear that if DANTE module could be used for apoE-/- mouse at 7T. Here we demonstrated a sequence using DANTE dark-blood preparation combined with FLASH readout (DANTE-FLASH) for three-dimensional (3D) vessel wall imaging at 7 Tesla (T).

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