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Abstract #2206

Improved fast multi-slice myocardial T1 mapping (FAST1) for full left ventricular coverage in three breathholds

Li Huang1, Radhouene Neji1,2, Muhammad Sohaib Nazir1, John Whitaker1, Filippo Bosio1, Amedeo Chiribiri1, Reza Razavi1, and S├ębastien Roujol1

1School of Biomedical Engineering and Imaging Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom, 2MR Research Collaborations, Siemens Healthcare Limited, Frimley, United Kingdom

Modified Look-Locker inversion recovery (MOLLI) is a commonly used approach for myocardial T1 mapping, and yields high precision as well as reproducibility. This technique requires one breathhold per slice, resulting in prolonged examination time when full left ventricular coverage is required. Our previously developed fast multi-slice myocardial T1 mapping (FAST1) technique showed potential for time-efficient full left ventricular coverage. In this work, the FAST1 sequence is further improved using Bloch-equation-based fitting for higher T1 accuracy and heart-rate independence. Compared to MOLLI, the proposed new FAST1 can yield higher T1 accuracy, enhanced tolerance to T2 and heart-rate variations, as well as similar repeatability and T1 map quality at 1.5T.

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