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Abstract #2317

Correlation of Multiparametric MRI with extracellular pH mapping in a Rabbit Model for Liver Cancer

Dana C Peters1, Lynn J Savic1, Steffen Huber1, John J Walsh1, Isabel Schobert1, Lucas Adam1, Nina Tritz1, Fahmeed Hyder1, Mingde Lin1, James S Duncan1, Douglas Rothman1, Albert J Sinusas1, Julius Chapiro1, R. Todd Constable1, and Daniel Coman1

1Yale University, New London, CT, United States

Hepatocellular Carcinoma (HCC) was studied using multiparametric MRI in a rabbit liver tumor model, comparing native T1 and T2* mapping, ADC, and dynamic contrast enhanced parameters, with extracellular pH maps. Tumor heterogeneity was well characterized by parametric mapping.

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