Abstract #2317

Correlation of Multiparametric MRI with extracellular pH mapping in a Rabbit Model for Liver Cancer

Dana C Peters¹, Lynn J Savic¹, Steffen Huber¹, John J Walsh¹, Isabel Schobert¹, Lucas Adam¹, Nina Tritz¹, Fahmeed Hyder¹, Mingde Lin¹, James S Duncan¹, Douglas Rothman¹, Albert J Sinusas¹, Julius Chapiro¹, R. Todd Constable¹, and Daniel Coman¹

¹Yale University, New London, CT, United States

Hepatocellular Carcinoma (HCC) was studied using multiparametric MRI in a rabbit liver tumor model, comparing native T1 and T2* mapping, ADC, and dynamic contrast enhanced parameters, with extracellular pH maps. Tumor heterogeneity was well characterized by parametric mapping.

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