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Abstract #2347

The Evaluation of Signal Intensity Related Predictors on T2-weighted for Pathological Complete Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer

Lijuan Wan1, Chongda Zhang2, and Hongmei Zhang2

1Department of Diagnostic Radiology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, 2National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

In order to evaluate the value of tumor signal intensity related parameters on T2-weighted magnetic resonance imaging (MRI) for pathological complete response (pCR) prediction, the signal intensity of tumor(SIT) and the muscle(SIM) were both measured automatically, SIT was defined as an absolute T2W signal intensity of tumor, and SIM was used to correct SIT, resulting in the relative T2W signal intensity(SIT/M), the reduction rate of SIT and SIT/M were calculated.Post-nCRT SIT(SITpost), post-nCRT SIT/M(SIT/Mpost), SITRR and SIT/MRR were proved to be significantly different between pCR and non-pCR, and The diagnositic efficiency is better in non-mucinous adenocarcinoma than mucinous adenocarcinoma.

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