Abstract #2382

In vivo MR imaging of pelvic lymph nodes at ultra-high magnetic field (7T)

Tom Scheenen^1,2, Bart Philips¹, Rutger Stijns¹, Ansje Fortuin¹, Marloes Van Der Leest¹, Mark Ladd³, Harald Quick^2,4, Jelle Barentsz¹, Stefan Rietsch^2,4, Sacha Brunheim^2,4, Stephan Orzada², and Marnix Maas¹

¹Radiology and Nuclear Medicine, Radboud university medical center, Nijmegen, Netherlands, ²Erwin L Hahn Institute, Essen, Germany, ³German Cancer Research Center, Heidelberg, Germany, ⁴University Hospital Essen, Essen, Germany

The presence of metastases in pelvic lymph nodes marks the transition from local to systemic disease in many primary cancers in the lower abdomen. This crucial step in disease progression determines prognosis and the choice of treatment. Detection of metastatic lymph nodes is currently done with invasive diagnostic surgery, but could profit from USPIO-enhanced MRI. In this 7T study we present an in vivo anatomical baseline of number, size and location of visible lymph nodes in healthy volunteers, as well as the feasibility of using USPIO-enhanced MRI to detect suspicious lymph nodes in patients with prostate and rectal cancer.

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