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Abstract #2385

Feasibility of Magnetic Resonance Fingerprinting of Glioblastoma Multiforme

Joshua D Kaggie1, Fulvio Zaccagna1, Mary McLean2, Dimitri A Kessler1, Guido Buonincontri3, Rolf F Schulte4, Amy Frary1, Martin J Graves1, Ferdia A Gallagher1, and Tomasz Matys1

1Department of Radiology, University of Cambridge, Cambridge, United Kingdom, 2Cancer Research UK, Cambridge, United Kingdom, 3IMAGO7 Foundation, Pisa, Italy, 4GE Healthcare, Munich, Germany

Magnetic Resonance Imaging (MRI) research seeks to establish fast, sensitive, repeatable, and quantitative methods. The reduction of MRI acquisition times is important for patients who have significant disease, such as glioblastoma multiforme (GBM), and therewith difficulties with lengthy scan sessions. Magnetic Resonance Fingerprinting (MRF) is a method that can enable fast quantitative T1 and T2 mapping by exploiting transient signals caused by the variation of pseudorandom sequence parameters. This work demonstrates the feasibility of MRF in three patients with GBM, showing two before and after gadolinium contrast.

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