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Abstract #2422

THE IMPACT OF MR IMAGES ACQUISITION PROCESS ON RADIOMIC FEATURES: PHANTOM STUDIES TO SUPPORT CLINICAL RESEARCH

Linda Bianchini1,2, Francesca Botta3, Daniela Anna Origgi3, Marta Cremonesi3, Paolo Arosio1,2, and Alessandro Lascialfari1,2

1Physics Department, Università degli Studi di Milano, Milan, Italy, 2INSTM, Milan, Italy, 3IEO, European Institute of Oncology IRCCS, Milan, Italy

Radiomic analysis of radiological images allows the extraction of quantitative features that can represent a support tool for clinical decision. The investigation of these features stability during the MR image acquisition process represents the aim of this study. The features short- and long-term repeatability was tested on a common MR phantom, imaged with the clinical protocol for gynecological imaging. The non-repeatable features were identified and can be excluded a priori in potential clinical studies. Simultaneously, a dedicated phantom was designed to mimic the pelvis and to investigate the stable features, especially the ones characterizing the texture of the imaged tissue.

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