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Abstract #2428

Robust 3D UTE T2* Mapping in MSK Using Fractional Order Bloch Equation

Dorottya Papp1, Gyula Kotek1, Stephan Breda1, Dirk H.J. Poot2, Edwin H.G. Oei1, and Juan Antonio Hernandez-Tamames1

1Radiology and Nuclear Medicine, Erasmus Medical Center, Rotterdam, Netherlands, 2Medical informatics, Erasmus Medical Center, Rotterdam, Netherlands

Determination of the T2* relaxation times with biexponential and monoexponential models has limitations, especially in case of complex, heterogeneous materials1. Using fractional order fitting model we can overcome these limitations8,9. In this model the introduced α parameter is the measure of the deviation from the monoexponential decay, and it accounts for micro-structural complexity. To evaluate the fractional order fitting, it was performed in patella tendon from UTE measurements, and we could demonstrate that compared to biexponential and monoexponential models it is less sensitive to variations to SNR.

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