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Abstract #2449

Image fusion of multiple independent MRI brain slabs to cover a whole Dugong brain in a small-bore, high-field pre-clinical scanner

Simone Zanoni1, Kenneth WS Ashwell2, and Andre Bongers1

1Biological Resources Imaging Laboratory, The University of New South Wales, Sydney, Australia, 2Department of Anatomy, The University of New South Wales, Sydney, Australia

This study we report about MRI of a fixed Dugong brain in a small bore pre-clinical MRI scanner. To enable the scanning of the brain that exceeds the sensitive scanner dimensions we propose a multi-slab imaging approach that uses an optimized image post-processing pipeline to merge independent slabs into a continuous high-resolution high-contrast 3D volume. We demonstrate that using this imaging and post-processing approach it is feasible to investigate relatively large objects in a pre-clinical scanner and retain full 3D information with the full benefit from the superior high resolution imaging capabilities of a high field pre-clinical scanner.

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