Abstract #2474

Feasibility of 7T 31P MRSI in lung tumors

Quincy van Houtum¹, Catalina Arteaga de Castro¹, Wybe van der Kemp¹, Joost Verhoeff², Jochem van der Voort van Zyp², and Dennis Klomp¹

¹Radiology, University Medical Center Utrecht, Utrecht, Netherlands, ²Oncology, University Medical Center Utrecht, Utrecht, Netherlands

In this study we show the feasibility of ³¹P MRSI acquisition from a lung carcinoma tumor in a patient using a ³¹P whole body birdcage coil at 7T. We showed that even without B₀ shimming, ³¹P spectra could be aligned and averaged to differentiate several metabolites, related to membrane metabolism, in the lung tumor. ³¹P MRSI has great potential for the detection of therapy response in lung tumor cancer, as often the tumor is still relatively large to obtain sufficient spectral signal.

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