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Abstract #2474

Feasibility of 7T 31P MRSI in lung tumors

Quincy van Houtum1, Catalina Arteaga de Castro1, Wybe van der Kemp1, Joost Verhoeff2, Jochem van der Voort van Zyp2, and Dennis Klomp1

1Radiology, University Medical Center Utrecht, Utrecht, Netherlands, 2Oncology, University Medical Center Utrecht, Utrecht, Netherlands

In this study we show the feasibility of 31P MRSI acquisition from a lung carcinoma tumor in a patient using a 31P whole body birdcage coil at 7T. We showed that even without B0 shimming, 31P spectra could be aligned and averaged to differentiate several metabolites, related to membrane metabolism, in the lung tumor. 31P MRSI has great potential for the detection of therapy response in lung tumor cancer, as often the tumor is still relatively large to obtain sufficient spectral signal.

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