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Abstract #2549

CSF Flow and Aging: An Early Marker of Pathology?

Arun Venkataraman1, Rashid Deane2, and Jianhui Zhong1

1Center for Advanced Brain Imaging and Neurophysiology, University of Rochester, Rochester, NY, United States, 2Neuroscience, University of Rochester Medical Center, Rochester, NY, United States

Phase Contrast-Magnetic resonance imaging (PC-MRI) provides detailed information on flow of spins, and has been applied to blood and cerebrospinal fluid (CSF) flow. In the field of CSF imaging, PC-MRI is mostly used as a clinical tool to look for frank CSF changes. However, subtle CSF changes are thought to occur in neurovascular pathologies, as well as neurodegenerative disorders such as AD. In addition, it has been shown that CSF flow may change during the aging process. In this abstract, we seek to select the optimal imaging parameters to investigate aging-related CSF changes.

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