Meeting Banner
Abstract #2559

Study of the cerebral blood flow metabolism in patients with Parkinson’s disease using arterial spin labeling MRI

Hong-Ying Zhang1 and Weiqiang Dou2

1Radiology, Northen Jiangsu people's hospital, Yangzhou, China, 2GE Healthcare, MR Research, Beijing, China

There are still debates on the alterations of subcortical metabolism in Parkinson’s disease. We performed 3D pseudo-continuous pulse ASL on PD and control groups. The absolute cerebral blood flow (CBF) values and relative CBF (rCBF) in subcortical regions were automatically extracted and calculated. We found widespread decreased absolute CBF in PD patients. However, the subcortical rCBF increased significantly. We conclude that widespread blood hypoperfusion in PD brain is absolute, and hyperperfusion in the subcortical brain regions is only relative to the whole brain level of patients themselves.

This abstract and the presentation materials are available to members only; a login is required.

Join Here