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Abstract #2652

HIV-Associated Cerebral Small Vessel Disease Measured by Quantitative Susceptibility Mapping

Kyle Douglass Murray1, Arun Venkataraman1, Pascal Spincemaille2, Lu Wang1, Yi Wang2, Madalina Tivarus1, Xing Qui1, Jianhui Zhong1, and Giovanni Schifitto1

1University of Rochester, Rochester, NY, United States, 2Cornell University, Ithaca, NY, United States

HIV-infected older individuals are at increased risk of developing cerebral small vessel disease (CSVD). Quantitative susceptibility mapping (QSM) can be used to asses tissue susceptibility, which can be a measure of CSVD. CSVD tends to occur more frequently in HIV-positive individuals. Limited information in the literature is available on HIV-associated changes in brain tissue susceptibility. In this abstract, we seek to discover relationships between HIV and QSM measures. Brain segmentation and region-based statistics were performed to discover region-based links between HIV and QSM measures and cardiovascular risk factors.

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