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Abstract #2708

A comparison of structural and diffusion-based MRI thalamus segmentation methods

Charles Iglehart1, Martin Monti2,3, Joshua A. Cain2, and Manojkumar Saranathan1,4

1Department of Electrical and Computer Engineering, University of Arizona, Tucson, AZ, United States, 2Department of Psychology, University of California, Los Angeles, Los Angeles, CA, United States, 3Department of Neurosurgery Brain Research Center, University of California, Los Angeles, Los Angeles, CA, United States, 4Department of Medical Imaging, University of Arizona, Tucson, AZ, United States

Automatic thalamus segmentation is a field of study with rapidly evolving applications. Both structural and diffusion weighted MRI can be used to drive parcellations of thalamus nuclei. In this study we present a comparison of leading structural and DWI-based segmentation techniques as implemented on a common set of subject datasets. Results for each are compared, both against an established anatomical atlas and each other. Spatial consistency of nuclei are examined in common template space. Finally, strengths and weaknesses of both techniques are discussed.

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