Abstract #2725

The effect of scan length on the assessment of perfusion using BOLD delay in ischemic stroke

Ayse Ceren Tanritanir¹, Kersten Villringer¹, Ivana Galinovic¹, Ulrike Grittner^2,3, Evgeniya Kirilina^4,5, Jochen B. Fiebach¹, Arno Villringer^6,7, and Ahmed A. Khalil^1,6,7

¹Center for Stroke Research, Charité University of Medicine, Berlin, Germany, ²Institute of Biometry and Clinical Epidemiology, Charité University of Medicine, Berlin, Germany, ³Berlin Institute of Health (BIH), Berlin, Germany, ⁴Department of Neurophysics, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany, ⁵Center for Cognitive Neuroscience, Free University, Berlin, Germany, ⁶Department of Neurology, Max Planck Institute for Human Cognitive and Brain, Leipzig, Germany, ⁷School of Mind and Brain, Humboldt University, Berlin, Germany

Hypoperfusion in acute stroke can be detected without exogenous contrast agents using BOLD delay. However the effect of scan duration on assessing perfusion using this method hasn’t been systematically evaluated. This study researched the effect of different scan lengths on diagnostic accuracy and image quality of BOLD delay maps while accounting for head motion. Our results revealed that scan time can be reduced to 3 min and 24 sec without compromising diagnostic power and image quality. However, lesion volumes were robust down to a scan length of 1 min and 8 sec.

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