Meeting Banner
Abstract #2747

A study of neurite orientation dispersion and density imaging in ischemic stroke

Zhenxiong Wang1, Shun Zhang1, Yang Fan2, and Wenzhen Zhu1

1Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, 2GE Healthcare China, Beijing, China

Neurite orientation dispersion and density imaging (NODDI) can quantitatively evaluate specific microstructural changes in terms of neurite density and orientation distribution of axons and dendrites. In the study, we attempt to demonstrate the feasibility of NODDI in characterizing the microstructural alterations in brain tissues during ischemic stroke and to compare its sensitivity with diffusion tensor imaging and diffusion kurtosis imaging. Results demonstrated that NODDI is a potential technique for quantitatively evaluating ischemic stroke and showed higher sensitivity compared with diffusion tensor imaging (DTI) and diffusion kurtosis imaging (DKI).

This abstract and the presentation materials are available to members only; a login is required.

Join Here