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Abstract #2763

Brain gray matter correlates of extraversion: A systematic review and meta-analysis of voxel-based morphometry studies

Han Lai1, Song Wang1, and Qiyong Gong1

1Huaxi MR Research Center (HMRRC), Chengdu, China

Extraversion is a fundamental personality dimension closely related to individuals’ physical and mental health. Although increasing studies have attempted to identify the neurostructural markers of extraversion but have yielded inconsistent and heterogeneous results. The current study aims to reach a comprehensive understanding of brain gray matter (GM) correlates of extraversion by using a systematic review and meta-analysis approach. Our review revealed a preliminary outline of the brain GM differences related to extraversion in distributed brain regions. Our meta-analysis of voxel-based morphometry studies identified six core brain regions correlated with extraversion and revealed the potential effect of gender and age.

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