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Abstract #2851

The comparison of L-FBPA PET/MR and PET/CT for BNCT treatment evaluation

Yi-Wen Lo1, Ko-Han Lin1, Yi-Wei Chen2, Rong-Hong Jhou1, Chien-Ying Li1, Li-Chen Shen3, Bang-Hung Yang 1, Chi-Wei Chang1, and Wen-Sheng Huang1

1Department of Nuclear Medicine, Taipei Veterans General Hosptial, Taipei City, Taiwan, 2Department of Radiation Oncology, Taipei Veterans General Hosptial, Taipei City, Taiwan, 3Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei City, Taiwan

We hypothesized that o-fluoro-L-p-boronophenylalanine (L-18FPBA) PET/MR could provide more precise treatment planning for Boron neutron capture therapy (BNCT) compared with L-18FBPA PET/CT. We implemented the phantom trial to measure the radioactivity correlation between PET/CT and PET/MR. Results have high comparability. We accessed patients who were potentially eligible for BNCT with same paradigms. The initial results represented acceptable correlation between these two modalities. Furthermore, because of high sensitivity and sophisticated imaging resolution, medics can easy to organize the more accurate treatment planning. In conclusion, PET/MR provides comparable L-18FBPA quantitative measurement and more diagnostic accuracy than PET/CT.

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