Metastases of nasopharyngeal carcinoma (NPC) in lymph nodes is not uncommon at initial diagnosis, thus the differentiation of the metastatic and reactive lymph nodes is important in accurate staging and precise administration for patients. In current study, a novel MRI quantification method named synthetic MRI was applied to estimate the relaxation values of 71 and 57 metastatic and lymph nodes in 40 patients with NPC, respectively. Our results showed that the relaxation values of lymph nodes were significant different between metastatic and reactive lesions. Moreover, the ration of T1/T2 showed encouraging diagnosis efficiency in differentiation of those two lymph nodes.
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