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Abstract #2952

The application of Synthetic MRI in differentiation of metastatic and reactive lymph nodes in patients with nasopharyngeal carcinoma: a preliminary study

Liangru Ke1, Tie-bao MENG1, Hui-ming LIU1, Long Qian2, Bing Wu2, Hui Li1, Yun He1, Hao-qiang HE1, and Chuan-miao XIE1

1Department of Medical Imaging, Sun Yat-sen University Cancer Center, Guangzhou, China, 2GE Healthcare, MR Research China, Beijing, China

Metastases of nasopharyngeal carcinoma (NPC) in lymph nodes is not uncommon at initial diagnosis, thus the differentiation of the metastatic and reactive lymph nodes is important in accurate staging and precise administration for patients. In current study, a novel MRI quantification method named synthetic MRI was applied to estimate the relaxation values of 71 and 57 metastatic and lymph nodes in 40 patients with NPC, respectively. Our results showed that the relaxation values of lymph nodes were significant different between metastatic and reactive lesions. Moreover, the ration of T1/T2 showed encouraging diagnosis efficiency in differentiation of those two lymph nodes.

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