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Abstract #2980

Short- and long-term reliability of BOLD signal change induced by breath holding: Comparison and validation at 1.5T and 3T

Hui-Chieh Yang1, Jyun-Ru Chen1, Chun-Ming Chen2, Yen-Chih Huang2, and Shin-Lei Peng1

1Department of Biomedical Imaging and Radiological Science, China Medical University, Taichung, Taiwan, 2Department of Radiology, China Medical University Hospital, Taichung, Taiwan

cerebrovascular reactivity (CVR) plays important role in the normalization and/or correction of functional magnetic resonance imaging (fMRI) data. But its reliability at the relatively lower field strengths such as 1.5T, to our knowledge, no study has systematically been conducted to date. By performing the systemic evaluations to compare the short- and long-term reliability of BH-induced CVR at 1.5T and 3T, we found reliable measurements of hemodynamic lag of the BOLD response, t-statistics, and activated cortical gray matter at both field strengths, suggesting that CVR measurement can be performed equally well at 1.5T and 3T.

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