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Abstract #3003

Decreased Brain Temperature in Former NFL Athletes

Tyler Chazan Starr1,2, Molly Charney1,2, Michael Alosco3, Jeffrey Qu1,2, Eduardo Coello1,2, Huijun Liao1,2, Inga Koerte4,5,6, David Kaufmann4,6, Martha Shenton1,4,5,7, Robert Stern3, and Alexander Lin1,2,4

1Radiology, Brigham and Women's Hospital, Boston, MA, United States, 2Center For Clinical Spectroscopy, Brigham and Women's Hospital, Boston, MA, United States, 3Boston University, Boston, MA, United States, 4Psychiatry Neuroimaging Laboratory, Brigham and Women's Hospital, Boston, MA, United States, 5Psychiatry, Massachusetts General Hospital, Boston, MA, United States, 6Child and Adolescent Psychiatry, Ludwig-Maximilians-Universität, Munich, Germany, 7VA Boston Healthcare System, Brockton, MA, United States

Currently, Chronic Traumatic Encephalopathy (CTE) is only diagnosed post-mortem, therefore advanced imaging has an opportunity to identify biomarkers for this disease. This study’s goal is to use Magnetic Resonance Spectroscopy (MRS) and MR Thermography (MRT) to measure cerebral temperature differences between retired former NFL players (n = 50) suspected of CTE and controls (n = 13). The NFL players were found to have lower brain temperature than the controls (p = 0.0340). These finding suggest there is a metabolic difference between those suspected of CTE and healthy controls.

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