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Abstract #3007

Monitoring subtle brain structural changes following concussion through advanced texture analysis of standard MRI scans

Munib Ali1, Shrushrita Sharma1, Glen Pridham1, Shahnewaz Hossain1, Mike Jarrett2, Jack Taunton2, David D.K. Li2, Alex Rauscher2, and Yunyan Zhang1

1University of Calgary, Calgary, AB, Canada, 2University of British Columbia, Vancouver, BC, Canada

Concussion is a severe health problem and occurs extremely common in contact sports. Clinical MRI is typically used to detect brain abnormalities following injury. However, focal brain pathologies are rarely found. We applied a local spatial frequency-based texture analysis method to evaluate whether invisible MRI changes exist and how they evolve following concussion. Results show that T2 texture spectra decreased uniformly at 2 weeks, continuing at 2 months before recovering thereafter towards baseline in concussed subjects. There were no changes in the non-concussed groups. Advanced texture analysis of clinical MRI may help monitor subtle brain structural changes following concussion.

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