Abstract #3019

Detection of abnormal cortical morphology in children and adolescence with intermittent exotropia by anatomic magnetic resonance imaging

Xi Wang¹, Lu Lu², Shi Tang², Xiaohang Chen³, Meng Liao¹, Qiyong Gong², Xiaoqi Huang², and Longqian Liu¹

¹Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu, China, ²Huaxi MR Research Center (HMRRC), Department of Radiology, West China Hospital, Sichuan University, Chengdu, China, ³Department of Optometry and Visual Science, West China Hospital, Sichuan University, Chengdu, China

The current study used anatomic magnetic resonance (MR) imaging to evaluate cortical structure alterations, age-related cortical and structural co-variance differences between children with intermittent exotropia (IXT) and healthy controls. The morphologic changes in the visual cortex and associations cortices, different anatomical-age correlation, and abnormal structural co-variance were detected in IXT group. These findings suggest possible disruptions of the cortical visual networks and the cortical maturation in IXT.

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