Abstract #3057

Association between T1rho relaxation time and iron deposition among AD patients and normal controls

Chun Ki Franklin Au¹, Jill Abrigo¹, Chung Tong Vincent MOK², Wing Chi Lisa AU², and Weitian Chen¹

¹Department of Imaging and Interventional Radiology, The Chinese University of Hong Kong, Hong Kong, Hong Kong, ²Department of Medicine & Therapeutics, Chinese University of Hong Kong, Hong Kong, Hong Kong

In this study, we investigated the relationship of iron deposition and T1rho measurement in thalamus among AD patients and healthy controls. Despite the theory indicates elevated iron concentration can decrease T1rho value, we did not observe obvious correlation between iron content and T1rho in this study. This can be due to the fact that the change of iron level is not significant enough to alter T1rho and/or other confounding factors.

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