Abstract #3109

Improved Structural Imaging of the Default Mode Network on the Compact 3T

Thomas Welton¹, Matthew Lyon¹, Jerome J Maller^1,2, Myung-Ho In³, Ek-Tsoon Tan³, Matt A Bernstein⁴, Erin M Gray⁴, Yunhong Shu⁴, John Huston⁴, and Stuart M Grieve^1,5

¹Sydney Translational Imaging Laboratory, Heart Research Institute, University of Sydney, Sydney, Australia, ²GE Healthcare, Richmond, Melbourne, Victoria, Australia, ³GE Global Research, Niskayuna, NY, United States, ⁴Department of Radiology, Mayo Clinic, Rochester, MN, United States, ⁵Department of Radiology, Royal Prince Alfred Hospital, Sydney, Australia

We compared diffusion MRI tractographic representations of the default mode network using high-angular resolution scans from the Compact 3T with high-performance gradients to equivalent data acquired on a standard clinical scanner. Overall performance in terms of strength, accuracy and visualisation of the DMN was superior for the Compact 3T data, with improved global tracking performance and improved measurement of weaker connections.

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