Quantitative Susceptibility Mapping has been shown to be capable of making estimates of venous oxygen saturation ($$$Y_v$$$) which are comparable to those obtained using MR methods such as calibrated BOLD. While there have been a few studies which have considered optimal acquisition parameters for QSM1,2 none have focussed on the specific case of deoxyhaemoglobin. In this work, we propose a protocol for which voxel dimensions, final echo time, and readout polarity have been optimised. Demonstrations of reasonably precise estimates of which are in line with the broader literature recommend suitability of the protocol for future studies.
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