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Abstract #3115

Optimisation of QSM measurements of venous oxygen saturation

John McFadden1, Julian Matthews2, Maélène Lohézic3, Geoff JM Parker1, and Laura Parkes1

1Division of Neuroscience and Experimental Psychology, Faculty of Biology, Medicine and Health, Stopford Building, University of Manchester, Manchester, United Kingdom, 2Division of Neuroscience and Experimental Psychology, Faculty of Biology, Medicine and Health, The Wolfson Molecular Imaging Centre, University of Manchester, Manchester, United Kingdom, 3Applications and Workflow, GE Healthcare, Manchester, United Kingdom

Quantitative Susceptibility Mapping has been shown to be capable of making estimates of venous oxygen saturation ($$$Y_v$$$) which are comparable to those obtained using MR methods such as calibrated BOLD. While there have been a few studies which have considered optimal acquisition parameters for QSM1,2 none have focussed on the specific case of deoxyhaemoglobin. In this work, we propose a protocol for which voxel dimensions, final echo time, and readout polarity have been optimised. Demonstrations of reasonably precise estimates of which are in line with the broader literature recommend suitability of the protocol for future studies.

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