Abstract #3157

A preliminary assessment of the relationship of radial diffusivity of the fornix to future episodic memory performance in Multiple Sclerosis

Katherine A Koenig¹, Jian Lin¹, Daniel Ontaneda², Kedar Mahajan², Jenny Feng², Stephen M Rao³, Sanghoon Kim¹, Stephen Jones¹, and Mark J Lowe¹

¹Imaging Sciences, The Cleveland Clinic, Cleveland, OH, United States, ²Neurological Institute, The Cleveland Clinic, Cleveland, OH, United States, ³Schey Center for Cognitive Neuroimaging, The Cleveland Clinic, Cleveland, OH, United States

Here we present a preliminary report assessing the relationship of DTI measures of the fornix to future episodic memory in patients with multiple sclerosis (MS). We find that radial diffusivity of the fornix is longitudinally related to visual spatial episodic memory. This finding suggests this measure is appropriate to investigate as a potential predictive marker of cognitive decline.

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