Meeting Banner
Abstract #3240

Clinical reliability of 3D whole-brain vessel wall imaging in patients with intracranial atherosclerotic disease: a comparison with conventional targeted imaging

Na Zhang1, Xinfeng Liu1,2, Qi Yang3, Shlee S. Song4, Zhenliang Xiong1,5, Lei Zhang1, Hairong Zheng1, Xin Liu1, and Zhaoyang Fan3,6

1Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China, 2Department of Radiology, Guizhou Provicial People's Hospital, Guiyang, China, 3Biomedical Imaging Research Institute, Cedars Sinai Medical Center, Los Angeles, CA, United States, 4Department of Neurology, Cedars Sinai Medical Center, Los Angeles, CA, United States, 5Guizhou University School Of Medicine, Guiyang, China, 6Department of Medicine, University of California, Los Angeles, CA, United States

Conventional intracranial MR vessel wall imaging (VWI) techniques based on 3D turbo spin-echo (TSE), with a thin, oblique slab to specifically target a limited imaging volume, have been shown to be reliable in quantifying vessel morphology of intracranial atherosclerotic disease (ICAD). Recently, 3D whole-brain VWI was proposed and optimized offering large spatial coverage, improved cerebrospinal fluid suppression, and enhanced T1 weighting and exhibits excellent reproducibility in quantification of vessel dimensions in healthy volunteers. This study is to further evaluate the clinical reliability of 3D whole-brain VWI in patients with ICAD via a comparison with 3D targeted VWI and 2D TSE.

This abstract and the presentation materials are available to members only; a login is required.

Join Here