Meeting Banner
Abstract #3242

Highly Accelerated Whole Brain Isotropic 0.5mm Intracranial Vessel Wall Imaging with Nonlocal Denoising and Super Resolution Enhancement

Zechen Zhou1, Baocheng Chu2, Jie Sun2, Niranjan Balu2, Mahmud Mossa-basha2, Thomas Hatsukami2,3, Peter Börnert4, and Chun Yuan2,5

1Philips Research North America, Cambridge, MA, United States, 2Department of Radiology, University of Washington, Seattle, WA, United States, 3Department of Surgery, Division of Vascular Surgery, University of Washington, Seattle, WA, United States, 4Philips Research Hamburg, Hamburg, Germany, 5Center for Biomedical Imaging Research, Department of Biomedical Engineering, Tsinghua University, Beijing, China

The three-dimensional (3D) turbo spin echo (TSE) sequence with variable flip angle (VFA) has proven to be clinically useful for high resolution intracranial vessel wall imaging (VWI) at 3T. In this study, a T1 weighted 3D TSE sequence was optimized for whole brain isotropic 0.5mm intracranial VWI in 8mins28secs. The optimized VFA design improves the flow suppression in small vessels and the nonlocal denoising effectively reduces the noise amplification after super resolution enhancement while improving the vessel wall boundary definition. This combined imaging and post-processing technique provides a promising tool for intracranial atherosclerosis and stroke investigation.

This abstract and the presentation materials are available to members only; a login is required.

Join Here