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Abstract #3285

The temporo-insular projection system: a multisubject fiber tractography study using connectome diffusion data

Ahmed Radwan1, Pieter Nachtergaele2, Stijn Swinnen2, Thomas Decramer2, Mats Uytterhoeven2, Johannes Van Loon2, Tom Theys2, and Stefan Sunaert1

1Department of Imaging and pathology, Translational MRI, KU Leuven, Leuven, Belgium, 2Department of Neurosciences, Research group experimental neurosurgery and neuroanatomy, KU Leuven, Leuven, Belgium

The precise structural connections between the amygdala, anterior temporal pole and insula remain poorly understood. These connections have been described with ex-vivo dissection, however the diffusion-based counterparts to these bundles haven’t been described in detail. In a recent study (currently under review) we investigated these connections with ex-vivo dissection on 11 brain specimens. We also explored the possibility of reconstructing the bundles found on dissection with Diffusion MRI. Here we demonstrate the results obtained for reconstructing these white matter connections using 20 randomly selected healthy participants of the HCP young adults data release.

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