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Abstract #3361

Imaging Cortical Columns in Gray Matter with Sub-Millimeter isotropic DTI

Iain P Bruce1, Christopher Petty1, and Allen W Song1

1Duke University Medical Center, Durham, NC, United States

The microarchitecture in gray matter of the human brain is comprised of short (<3 mm) cortical columns that traverse six cortical layers. To most accurately delineate these columns in-vivo, it is essential to achieve isotropic spatial resolutions on the order of 0.8 mm or less. In this study, we present a means of acquiring diffusion tensor imaging data with ultrahigh spatial resolution to effectively characterize the complex architecture of gray matter.

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