Abstract #3416

Difference in Tensor Metrics between the Survived and Infarcted Penumbra by Reperfusion in a Rat Model of Cerebral Ischemia

Yu-Chieh Jill Kao^1,2,3, Jun Tazoe^3,4, Chia-Feng Lu⁵, Bao-Yu Hsieh⁶, and Cheng-Yu Chen^1,2,3,7

¹Neuroscience Research Center, Taipei Medical University, Taipei, Taiwan, ²Department of Radiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, ³Translational Imaging Research Center, Taipei Medical University Hospital, Taipei, Taiwan, ⁴Department of Radiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan, ⁵Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan, ⁶Department of Biomedical Imaging and Radiological Science, China Medical University, Taichung, Taiwan, ⁷Department of Medical Imaging, Taipei Medical University Hospital, Taipei, Taiwan

We demonstrated significant difference in FA and q-value between destined-survived and destined-infarcted penumbral tissue by reperfusion in transient MCA occlusion animals, which may imply the possible application of DTI-MRI in the evaluation of salvageable tissue before mechanical thrombectomy for acute stroke.

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