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Abstract #3475

Optimization of b-values for estimation of IVIM D and f

Oscar Jalnefjord1,2, Mikael Montelius1, Göran Starck1,2, and Maria Ljungberg1,2

1Department of Radiation Physics, University of Gothenburg, Gothenburg, Sweden, 2Department of Medical Physics and Biomedical Engineering, Sahlgrenska University Hospital, Gothenburg, Sweden

IVIM parameter estimation restricted to D and f (avoiding D*) has gained increased popularity. In this study we propose a framework for optimization of b-value schemes for this application. We show that optimized b-values schemes contain exactly three unique b-value, regardless of the total number of acquisitions, and that parameter estimation uncertainty can be substantially reduced by the use of the optimized b-value schemes.

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