Abstract #3475

Optimization of b-values for estimation of IVIM D and f

Oscar Jalnefjord^1,2, Mikael Montelius¹, Göran Starck^1,2, and Maria Ljungberg^1,2

¹Department of Radiation Physics, University of Gothenburg, Gothenburg, Sweden, ²Department of Medical Physics and Biomedical Engineering, Sahlgrenska University Hospital, Gothenburg, Sweden

IVIM parameter estimation restricted to D and f (avoiding D*) has gained increased popularity. In this study we propose a framework for optimization of b-value schemes for this application. We show that optimized b-values schemes contain exactly three unique b-value, regardless of the total number of acquisitions, and that parameter estimation uncertainty can be substantially reduced by the use of the optimized b-value schemes.

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